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Liga Zvejniece Selected Research

4-amino-3-phenylbutyric acid (phenibut)

9/2020Safety and Tolerability of the Anxiolytic and Nootropic Drug Phenibut: A Systematic Review of Clinical Trials and Case Reports.
1/2020Mitochondrial-Protective Effects of R-Phenibut after Experimental Traumatic Brain Injury.
11/2016The neuroprotective effects of R-phenibut after focal cerebral ischemia.
10/2015R-phenibut binds to the α2-δ subunit of voltage-dependent calcium channels and exerts gabapentin-like anti-nociceptive effects.
3/2008Comparative pharmacological activity of optical isomers of phenibut.

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Liga Zvejniece Research Topics

Disease

4Seizures (Absence Seizure)
01/2021 - 09/2010
4Encephalitis (Encephalitis, Rasmussen)
04/2010 - 12/2005
3Necrosis
10/2020 - 08/2009
3Pain (Aches)
08/2009 - 10/2006
3Inflammation (Inflammations)
12/2007 - 12/2005
2Traumatic Brain Injuries (Traumatic Brain Injury)
10/2021 - 01/2020
2Hypoxia (Hypoxemia)
11/2020 - 01/2020
2Body Weight (Weight, Body)
01/2017 - 12/2007
2Brain Ischemia (Cerebral Ischemia)
11/2016 - 09/2011
2Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
11/2016 - 09/2011
1Adenocarcinoma
01/2022
1Neurodegenerative Diseases (Neurodegenerative Disease)
10/2021
1Sleepiness
09/2020
1Substance-Related Disorders (Drug Abuse)
09/2020
1Schizophrenia (Dementia Praecox)
12/2019
1Cognitive Dysfunction
10/2019
1Hyperglycemia
01/2017
1Nervous System Diseases (Neurological Disorders)
01/2017
1Obesity
01/2017
1Weight Gain
01/2017
1Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2017
1Stroke (Strokes)
11/2016
1Neuralgia (Stump Neuralgia)
10/2015
1Hyperalgesia
10/2015
1Infarction (Infarctions)
09/2011
1Diabetes Complications
08/2009
1Type 2 Diabetes Mellitus (MODY)
08/2009
1Coronary Occlusion
08/2009
1Neuroinflammatory Diseases
01/2004

Drug/Important Bio-Agent (IBA)

54-amino-3-phenylbutyric acid (phenibut)IBA
09/2020 - 03/2008
4MelanocortinsIBA
10/2006 - 01/2004
3Proteins (Proteins, Gene)FDA Link
01/2022 - 01/2017
33-(2,2,2-trimethylhydrazine)propionateIBA
09/2011 - 08/2009
3Nitric Oxide (Nitrogen Monoxide)FDA Link
04/2010 - 06/2006
3Melanocortin Receptors (Melanocortin Receptor)IBA
12/2007 - 12/2005
3Peptides (Polypeptides)IBA
10/2006 - 01/2004
2Neuroprotective AgentsIBA
10/2021 - 11/2016
2Sigma-1 ReceptorIBA
10/2021 - 01/2017
2LigandsIBA
10/2021 - 01/2017
2Pentylenetetrazole (Metrazol)IBA
01/2021 - 10/2015
2imidazole mustard (BIC)IBA
01/2021 - 01/2017
2Interleukin-1beta (Interleukin 1 beta)IBA
10/2020 - 04/2010
2Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
10/2020 - 04/2010
2Dizocilpine Maleate (Dizocilpine)IBA
12/2019 - 10/2019
2Glucose (Dextrose)FDA LinkGeneric
01/2017 - 08/2009
2Blood Glucose (Blood Sugar)IBA
01/2017 - 08/2009
2NF-kappa B (NF-kB)IBA
04/2010 - 12/2005
2LipopolysaccharidesIBA
04/2010 - 12/2007
2beta-MSHIBA
10/2006 - 12/2005
1GABA-B ReceptorsIBA
01/2021
1BicucullineIBA
01/2021
1Glutamic Acid (Glutamate)FDA Link
11/2020
1Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone (FCCP)IBA
11/2020
1CalciumIBA
01/2020
1N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
12/2019
1S-phenylpiracetamIBA
01/2017
12- (4- morpholino)ethyl- 1- phenylcyclohexane- 1- carboxylateIBA
01/2017
1N,N- dipropyl- 2- (4- methoxy- 3- (2- phenylethoxy)phenyl)ethylamine monohydrochlorideIBA
01/2017
1Appetite Depressants (Anorectics)IBA
01/2017
1LeptinIBA
01/2017
11- (3,4- dimethoxy- 2- - chlorobenzylideneamino)guanidineIBA
04/2010
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
04/2010
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
04/2010
1Fatty Acids (Saturated Fatty Acids)IBA
08/2009
1FructosamineIBA
08/2009
1Carnitine (L-Carnitine)FDA LinkGeneric
08/2009
1Phenylephrine (Neo-Synephrine)FDA LinkGeneric
08/2009
1CarbohydratesIBA
08/2009
1Antidepressive Agents (Antidepressants)IBA
03/2008
1melanotan-IIIBA
12/2007
1Type 4 Melanocortin Receptor (Melanocortin-4 Receptor)IBA
12/2007
1Melanocyte-Stimulating Hormones (MSH)IBA
10/2006
1Analgesics (Analgesic Drugs)IBA
10/2006
1Indomethacin (Indometacin)FDA LinkGeneric
10/2006
1gamma-MSHIBA
10/2006
1Pharmaceutical PreparationsIBA
10/2006
1Formaldehyde (Formol)FDA Link
10/2006
1alpha-MSHIBA
10/2006
1Hormones (Hormone)IBA
10/2006
1Type 3 Melanocortin ReceptorIBA
06/2006